Spectral Analysis for Kinetic Estimation

SAKE is a stand-alone license-free software which implements the state-of-the-art Spectral Analysis methods for PET quantification. SAKE has been thought as much user-friendly as possible, to be used by expert and not expert ICT users.

SAKE is currently used by more than 50 research centres worldwide and it is being taught within the course “Experimental Design and Practical Data Analysis in Positron Emission Tomography”, held at King’s College London (UK).

LINK TO DOWNLOAD (Full video manual available in YouTube)

Some references on Spectral Analysis for PET imaging:

  • Veronese, Mattia, et al. “Spectral analysis of dynamic PET studies: a review of 20 years of method developments and applications.” Computational and mathematical methods in medicine (2016).
  • Veronese, Mattia, et al. “SAKE: a new quantification tool for positron emission tomography studies.” Computer methods and programs in biomedicine 111.1 (2013): 199-213.
  • Veronese, Mattia, et al. “Parametric Mapping for TSPO PET Imaging with Spectral Analysis Impulsive Response Function.” Molecular Imaging and Biology (2021): 1-12.
  • Veronese, Mattia, et al. “A spectral analysis approach for determination of regional rates of cerebral protein synthesis with the L-[1-11C] leucine PET method.” Journal of Cerebral Blood Flow & Metabolism 30.8 (2010): 1460-1476.