Multimodal Environment for Neuroimaging and Genomic Analysis

MENGA is a platform for the integration of imaging data and Allen Human Brain Atlas mRNA data. MENGA aims to provide a comprehensive environment to investigate correlation patterns between various imaging modalities and gene expression profiles based on the Allen Brain Atlas.

The project comes from a collaboration between the Department of Information Engineering (DEI), University of Padova with the Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King’s College, London (UK).

MENGA is a Matlab-based software package, that can be freely downloaded through NITRC portal.

References:

  • Rizzo G, Veronese M, Expert P, Turkheimer FE, Bertoldo A (2016) MENGA: A New Comprehensive Tool for the Integration of Neuroimaging Data and the Allen Human Brain Transcriptome Atlas. PLOS ONE. doi:10.1371/journal.pone.0148744
  • Rizzo G, Veronese M, Heckemann RA, Selvaraj S, Howes OD, Hammers A, Turkheimer FE, Bertoldo A. The predictive power of brain mRNA mappings for in vivo protein density: a positron emission tomography correlation study. J Cereb Blood Flow Metab. 2014 May;34(5):827-35. doi: 10.1038/jcbfm.2014.21.